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1、2023年申请国外博士 个人简历(CV) 第一篇：申请国外博士 个人简历(CV) XXX Gender:Male Date of Birth: 10/20/1987Add: Nanjing University of Information Science & Technology School of Environmental Science and EngineeringSchool Office No.219, Ningliu Road, Pukou District, Nanjing, Jiangsu Province, 210044, P.R.ChinaE-mail: Tel: 86
2、-*EducationSeptember 2023-Present lNanjing, China l l Research Experience lFebruary 2023-Present Research Projects: The modification of the antifungal Fluconazole; Synthesis of carbohydrate compounds containing -amino alcohol via Henry Reaction; The synthesis and applications of oxazolidinone compou
3、nds.Main Responsibility: Search literature, optimize experimental methods under the guidance; Carry out reactions and purify the products.lMarch-December 2023 1.Research Projects: Design and Applications of Functional Macrocyclic Compounds(College Students Science and Technology Innovation Training
4、Projects of Jiangsu Province (No.xxx and No.xxxx) 2.Chinese Patent: The Synthesis and Applications of Macrocyclic Compounds Containing The Structure of Arylamine(Application No.xxxxxxxxx.x).3.Publication Synthesis and characterization of the novel shape-persistent nanosized cavity macrocycle,synthet
5、ic metals 2023, XXX, XXXX-XXXX.Research Interests l Synthetic organic chemistry in natural products; l Asymmetric synthesis.English Proficiency l IELTS: 6.5(Listening 6.5, Reading 7.5, Writing 6, Speaking 6.5) Professional Skills Chemistry l Proficient in literature review, spectrum analysis and nor
6、mal laboratory techniques;l Enable to conduct reactions with air sensitive reagents using a double manifold;l Monitor reactions with TLC, HPLC, GC; l Purify and separate products using column chromatography.Computer l Specialized software: ChemBio Office, Origin, Endnote, etc.; l Literature searchin
7、g online.Extracurricular Activities and Awards l l l l l President Scholarship, NUIST, Oct.2023 Award of Pacemaker to Merit Student, NUIST, Oct.2023 Award of Excellent Student Cadre, NUIST, Oct.2023 Pei Zhi Scholarship, NUIST, Jan.2023 First Prize in the 2nd Chemical Experiment & Skills Contest of N
8、UIST, Jan.2023 Hobbies l Badminton, Jogging, Reading, Music 其次篇：CV英文个人简历 personal Information: Name: XXX Sex: Male Date of Birth: XX XXth XX place of birth: XX, p.R.China Marital Status: XX Health: Good Mobile :13XXXXXXX E-mail: wdjlw xiexiebang Objective: Application Engineer, Technical and Electro
9、nics Sales.Education Background: 2023.9?2023.6 XXXX.Bachelor of Electronic informationn engineering Major subjects: Circuit principle, Single Chip Computer principle and Application, Digital Electronic Technology, Analog Electronic Technology, Interfacing and Application of Computer, principle of Co
10、mmunication,Work Experiences: 2023.7-present XXX As a computer software engineer, Responsibilites includes : 1.Solving environmental problems on prototype computers.Conducte systems analysis on new computer profucts to ensure hardware,software and mechanical design integrity 2.And responsible for Sy
11、stem compatibility and integration test.Quickly diagnose causes of systems failures and malfunctions to ensure highest operating efficiencies,reliability,and quality performance standards.3.Assist engineers from Hp wIth installation and trobleshooting of Hp Bussiness pC software English Skills 1.pas
12、s CET-4 2.Have a good command of spoken and written English.Communicate and negociate with clients fluently in English.3.Skilled in reading documents relating to Electronics and Computer Others Independent and be able to work under pressue.Have coordination skills,teamwork spirit.Studious nature and
13、 dedication are my greatest strengths 第三篇：(CV)英文个人简历正规格式 DENG XIAO PENGMobile: XXXXXX;Email: XXXXXXX Career(Part-time & Intern in Australia) 2023.4-2023.9Australia Starmart Cleaning Co.Accountant Helped the company design and develop management software of staff database Assisted the Finance Manager
14、 in issuing series of financial invoices Reviewed and organized the companys financial statements and tax forms Delivered the bank documents and dealt with some daily routines of the office 2023.5-2023.1Australia Telecommunication Company(now Vodafone) Sales Representative for 3G Mobiles Worked for
15、the market survey and promotion of 3G new mobile products Participated in the sales and contract signing for new 3G mobiles Helped the company maintain good after-sale services for main customers 2023.10-2023.11CPA Australia OfficeTrainee Received professional trainings on corporate finance, account
16、ing and corporate management Assisted the office in completing the audit and reimbursement of monthly expenses Worked for some administration and logistics issues for the office 2023.7-2023.8IDP Education AustraliaStudent Representative, Marketing Department Discussed cooperation with Australian uni
17、versities in campus marketing issues Managed the distribution of stuff and gifts used for campus marketing and promotions Education 2023.9-2023.11The University of XXXXXXXXX, Australia Bachelor of Marketing(Business Administration & Marketing) 2023.9-2023.8XXXXXXX Australia Diploma and Certificate i
18、n Accounting(Accounting & Finance) Main Courses Corporate Finance, Accounting Principle, International Marketing,Marketing Research, Integrated Marketing Communications, Sales Management, Marketing of Service, Retail Marketing and Distribution, Consumer Behavior Strength English language skill: flue
19、nt in using English for work and communications Computer skills: proficient in using office software including Word, Excel, Powerpoint, Outlook, Access and Publisher Have mastered comprehensive expertise in business management, accounting and marketing, and have the ability of quick learning Fast ad
20、aptation to new working environment and dedicated to efficient team work OthersGender: male Height: 177CM DOB: Oct.1986 Hukou: XXXXX 第四篇：(CV)英文个人简历正规格式 DENG XIAO PENGMobile: XXXXXX;Email: XXXXXXX Name: Gender: male E-mail: Tel: Experience 2023-2023English intern in a poor mountain village elementary
21、 school.2023-2023college student union.Manage the things that used in some big event.Education 2023.9-presentstudy in Wenzhou University, major in Business English.Main Courses American CultureHistory and Anthology of English LiteratureMicro-economyReading Course in American and British News Publica
22、tions English-Chinese Translation The Art of Public Speaking A Survey: Major English-Speaking Countries Oral English Computer Skills Strength English language skill: fluent in using English for work and communications Fast adaptation to new working environment and dedicated to efficient team work St
23、rong experience in team building, project management and coordination.Project planning, budget control and manage deliverables on schedule.Business development and customer oriented communication.Interests Playing music, badminton, chatting with friends, reading, English films,writing. 第五篇：申请国外高校博士的
24、支配书 Research Interest Proposal I am the Doctor degree applicant Xu Zhiwei.From September 2023 to June 2023, I studied the laboratory medicine at Nantong University.In September 2023 I was recommended to the graduate school by the professors due to my excellent assessment.Through undergraduate studie
25、s, I contacted such theories as molecular biology, cellular biology , immunology and so on.However, keenly conscious that my current acquisition is far from enough for me to meet the needs of the fast developing medicine, I am eager to pursue further studies in Chinese medical sciences.With my hard
26、working, I know about the basic knowledge of medical immunology.Up to now, I have known a lot about the University of Macau.The graduate school of university plays a prominent role in the academic research and transforms Macao into a knowledge-based society.I am dedicated to pursuiting medical resea
27、rch and hoping to come to the university of Macau for rich experiences and success in PhD program.I am now applying for Chinese Medical Science in the University.This planned research has the following aims: The deubiquitinating enzyme USP14 has been identified and biochemically studied, but its mec
28、hanisms in cancer remains to be elucidated.Protein glycosylation with O-linked N-acetylglucosamine(O-GlcNAc)is a reversible post-translational modification occurring onserine or threonine residues.Intriguingly, it has been observedthat O-GlcNAcylation is particularly abundant on cancer cells.The aim
29、 of this study was to evaluate the O-GlcNAcylation of USP14 in patients with cancer and to define its mechanisms in cancer cell proliferation and apoptosis.a.To demonstrate that O-GlcNAcylation of USP14.b.To explore Interplay between USP14 O-GlcNAcylation and phosphorylation c.To determine how O-Glc
30、NAcylation regulates metabolic reprogrammingand Signaling in cancer cells.d.To test whether O-GlcNAcylation regulates proliferation and apoptosis.2.Research Context Deregulating cellular energetics is emerging as a characteristichallmark of cancer cells.Withinsuch cells, glucose and glutamine are us
31、ed at an increasedrate, resulting in the production ofATP in a manner independent of oxygen concentration.Elevated glucose and glutamine flux areneeded not only to serve the energetic demands of cancer cells,but also to provide the essential carbon and nitrogen used inmacromolecule synthesis, fuelin
32、g the rapid growth and proliferation seen in tumors.This increasein glucose and glutamine uptake can alter multiple metabolicand signaling pathways in cancer cells, including for examplethe hexosamine biosynthetic pathway(HBP).The HBP relies on glucose and glutamine uptake, and approximately 3%5% of
33、 the total glucose entering a cell is shunted intothis pathway.This critical metabolite isrequired for the biosynthesis of a variety of extracellular glycopolymers, including both N-and O-glycans, however, it also serves as the substrate for O-linked b-N-acetlyglucosamine (O-GlcNAc) transferase (OGT
34、).O-GlcNAcylation is directly involved in growth hormone(gibberellic acid)signalling in plants, and both SPY and SECRET AGENT(SEC)encode O-GlcNAc transferases.Mutations in either SPY or SECcause severe growth defects;simultaneous mutation of both genes islethal.Unlike plants, mammals and insects see
35、m to have only a single gene encoding the catalytic subunit of the O-GlcNAc transferase(OGT)Gene disruption in mice established that OGT is required forembryonic-stem-cell viability20.Tissue-targeted disruption in miceshowed that O-GlcNAcylation is essential to several cell types.OGTdeletion causes
36、hyperphosphorylation, which is followed by cell death, induces T-cell apoptosis and causes growth arrest infibro blasts.Crelox-mediated deletion of OGT in cultured fibroblastsresults in death as pre-existing OGT protein levels diminish.This modification can be removed by theglycoside hydrolase O-Glc
37、NAcase(OGA)that catalyzes cleavage of O-GlcNAc from proteins.This modification can alter protein functiondirectly or, in some cases, by competing with phosphorylationsites.O-GlcNAc and O-phosphate site-mapping studies suggest that there areat least four different types of dynamic interplay between O
38、-GlcNAcand O-phosphate.First, there is competitive occupancy at thesame site, for example that which occurs in the transcription factorc-Myc25 and oestrogen receptor-26, and on the oncoprotein SV-40 largeT-antigen27 and endothelial nitric oxide synthase28.Second, competitiveand alternative occupancy
39、 occur at adjacent sites, such as that observedin the tumour suppressor p53 and synapsin I.Third,there is a complex interplay whereby some O-phosphate attachmentsites on a given protein are the same as some O-GlcNAc sites, whereasothers are adjacent to, or even distant from, each other, such as on t
40、heC-terminal domain of RNA polymerase II and on cytokeratins32.The final type of interplay involves proteins in which this relationship has yet to be clearly defined.The interplay between O-GlcNAcand O-phosphate is also underscored by the recent finding that OGTtransiently forms complexes containing
41、 the catalytic subunit of proteinphosphatase 1(PP1c).Cancer cells, however, uptake glucose at a higher rateand produce lactic acid rather than metabolizing pyruvate throughthe tricarboxylic acid(TCA)cycle.This adaptive metabolic shift is termed the Warburg effect, leading to anaerobic glycolysis, an
42、d is thought toprovide an evolutionary advantage to cancer cells by providingboth increase bioenergetics and biosynthesis.Many protooncogenes(e.g., Ras and Myc)and tumor suppressors(e.g., p53)influence metabolism,and mutations in these genes can upregulateglucose uptake in cancer cells and promote a
43、 metabolic phenotype supporting tumor cell growth and proliferation.Elevatedglucose uptake in cancer cells can be applied to monitor the location of primary and metastatic tumor sites;for an example, usingF-18 fluorodeoxyglucose(FDG), a glucose analog, with a combination of positron emission tomogra
44、phy/computed tomography(PET/CT).Recent study has providedinsights into the mechanism ofpost-translational modification of molecules in cancer cells theregulation of many molecules and suggested important implications in cancer development.Additionally, lines ofevidence of global proteomic analysis h
45、avesuggested that post-translational modifications of USP14 are likely not limited to phosphorylation.Other forms of modifications, such asO-GlcNAcylationappear to occur as well,suggesting a more sophisticated regulatorynetwork of USP14.In this study, we would evidence that O-GlcNAcylation within ca
46、ncer cells regulates cancer cell metabolism via regulation of phosphorylation and its downstream target genes.Mechanistically, we wonder which signaling pathway has participated in the regulation.Furthermore, we will discuss whether decreased O-GlcNAcylation leads to reduced proliferation and apoptosis incancer cells.In addition, we hypothesized that human cancers containing high USP14 levels also containelevated OGT and O-GlcNAcylation.Importantly, we will explore in overallcancer patients, lower OGA expression correlates withpoor clinical outcome.Thus,w