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1、choice question 1.Immunological unresponsiveness to self antigens is called:A A.Tolerance B.Tolerogen C.Memory D.Acquired immunity 2.The signal transduction molecules associated with BCR are:B A.CD21 and CD81 B.Ig and Ig(CD79a and b).C.IgD and IgM D.ITAMs and ITIMs 3.T cells are MHC-restricted in th
2、eir ability to respond to antigen because:D A.All antigen must be processed and presented to activate lymphocytes B.During an infection,all cells in the body present antigen on MHC Class I C.MHC binds antigen more specifically than TCR does.D.TCR must recognize both antigen and MHC molecules.4.Posit
3、ive selection in the thymus is mediated by:A A.Thymic epithelial cells B.Macrophages C.Dendritic cells D B-cells 5.CD8 is a marker of:C A.B cells B.Helper-T cells C.cytotoxic T cell D.M 6.MHC class II molecules are found on:B A.Virtually all cells in the body B.B cells,DC and M C Virtually all nucle
4、ated cells in the body D.Only on virally-infected cells 7.Which of the following is NOT ture of CD4+and CD8+cell markers?D A.These are both surface glycoproteins expressed on T-cells B.These serve to distinguish different types of T-cells,e.g.,helper,suppressor and cytotoxic,from each other.C.These
5、are not found associated with immuogobulins D.Both of the markers are present on all T-cells 8.Dendritic cells are characterized by:D A.The presence of major basic protein B.expression of CD3 C.expression of IgM molecules D their interface between the innate and adaptive immune system 9.Opsonization
6、 of bacteria occurs through coating bacteria just with:A A.C3b B.C8 C.Membrane attack complex D.IgM 10.The following is characteristic of B cells but not T cells:D A.Class I MHC B.CD3 C.HIV virus receptor D.Surface immunoglobulin 11.The thymus is the site of initial differentiation for:D A.B cells B
7、.Erythrocytes C.Hematopietic stem cells D.T cells 12.The membrane attack complex consists of:C A.OH B.C3b2a,Bb C.C5b6789 D.Properdin 13.T-cells CD40L provides a costimulatory signal to B-cells by ligating:A A.CD40 B.MHC class II C.CD28 D.CD19 14.Immune complexes consist of:C A.Antibody plus compleme
8、nt B.basophil plus complement C antigen plus antibody D.antigen plus complement 15.Secondary antibody responses are better because:C A.They provide defense against inrelated antigens B.The antibody can be made by both T and B cells C.They are stronger and faster D.They do not require T-cell help 16.Which cell type produces antibodies:D A.Macrophages B.T-lymphocytes C.NK D.Plasma cells