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1、 Service Manual for MODEL 7180 AUTOMATIC ANALYZER Copyright Hitachi High-Technologies Corporation,2002.All rights reserved.Printed in Japan.Part No.751-9012 CONTENTS 1.Product Specifications 2.Troubleshooting 3.Flow Path Diagrams 4.ISE 5.Switch Settings 6.Functional Explanation 7.Motors,Detectors,Fu
2、ses and Solenoid Valves 8.Cross Wiring Reference 9.Maintenance and Inspection 10.Circuit Diagrams 11.Adjustment Specifications 12.Installation Manual 13.Other Unit 14.System Interface Chapter 1 Product Specifications 1.1 Configuration of Equipment Units.1-1 1.2 Specifications.1-4 1.2.1 General speci
3、fications.1-4 1.2.2 Sampling unit.1-5 1.2.3 Reagent unit.1-6 1.2.4 Reaction unit.1-6 1.2.5 Measurement unit(photometer).1-7 1.2.6 Measurement unit(ISE optional).1-7 1.2.7 Calculation unit.1-8 1.2.8 Installation conditions.1-9 1.2.9 Options.1-9 1-11.1 Configuration of Equipment Units Analytical unit
4、Control unit Printer Keyboard CRT PC 1-2 Top cover Reaction table Reagent disks Sample disks ISE unit ISE bottle PWB rack DC power supply unit Refrigerator 1-3 Water supply port Low-concentrated waste solutiondrain port High-concentrated waste solution drain port DOI PWB Relay PWB 1-41.2 Specificati
5、ons 1.2.1 General Specifications Item Details Configuration Analytical unit+Control unit Throughput 800 tests/hour max.(1200 tests/h max.when ISE unit is provided)Number of simultaneously analyzed tests 86 max.(89 max.when ISE unit is provided)Analytical methods 20,including end-point assay,2-point
6、assay,rate assay,ISE(optional)Required sample volume 1.5 to 35 l/test(0.1 l units)Reagents 1-4,20 to 270 l/test(0.1 l units)for each reagent Final volume:120 to 300 l/test Detergent 2 types(70 ml and 140 ml outside reagent disk)for cell and probe Reaction time 3,4,5,10,15,22 minutes(settable for eac
7、h test)Reaction temperature 37C0.1C Stir timing Immediately after each reagent is pipetted Data processing functions Automatic calibration,multipoint calibration,isozyme calibration,calibration point select function,photometry analysis calculation,rate analysis calculation,isozyme analysis,prozone c
8、heck in all analytical methods,serum index,sample blank correction,repeat limit check,test-to-test calculation,real-time QC,X-R control,automatic rerun function,calculation trace,test counting,data storage(total 10,000 routine and stat samples)Output ledgers Analysis results(monitoring format,report
9、ing format),worksheet,rerun list,calibration report,photometer check list,QC list,alarm trace,reaction process printing,analytical curve printing,operation data control printing,list of calibration results Support functions Reproduciability calculation,sleep mode,stat simple analysis function,operat
10、ion data control,sample type setting,host transmission function for each test,operator ID control function,online help function,batch setup function,remote maintenance correspondence function Printer Dot matrix,80 digits Display/Input CRT,touch screen,mouse,keyboard System interface RS232C 1-51.2.2
11、Sampling Unit Item Details Sample cup Hitachi standard sample cup,Hitachi trace amount sample cup Number of sample tracks Routine/stat samples(110),control/standard solution(57),detergent(3)Measures for stat sample 1)Sampling is started immediately upon request for stat samples.2)Immediate interrupt
12、 permitted even during routine analysis 3)Schedule for analysis in shortest time automatically laid out and executed 4)Results printed out immediately after completion of analysis Sampling mechanism Pipetting system with syringe driven by pulse motor Settable range:1.5 to 35 l/test,0.1-l pitch Dead
13、volume Standard 50 l,trace amount 30 l Dummy volume 12 l Pipetting modes 1)Standard:Discharges set volume of sample into cell.2)Predilution:Dilutes sample with water or diluent on reaction line.3)Water discharge:Discharges water as sample for reagent blank.Sample predilution Dilution on reaction lin
14、e for specified test(1.5 to 20 l repipetted)Diluent set on reagent disk,or system water used Standard predilution Up to 6 dilution levels preparable from one or more standards Dilution conditions conform to those for sample predilution.Detection of sample insufficiency Possible with electrostatic ty
15、pe liquid level sensor Sample identification Identification through barcode label(optional)Probe washing Washing of probe inside and outside with deionized water Program for washing with detergent settable 1-61.2.3 Reagent Unit Item Details Reagent disk Flatbed disk x 2 R1:45 positions,R2:44 positio
16、ns(One position is exclusively for Hitergent)Reagent cooling Water circulating type cooling unit incorporated,all positions kept cooled Reagent bottle 7 ml,20 ml and 70 ml Reagent pipetting mechanism Pipetting system with syringe driven by pulse motor Settable range:35 to 270 l/shot,0.1-l pitch Numb
17、er of reagent shots:4 max.(R1/R4,R2/R3)Dead volume 6 mm or less from reagent bottle exterior bottom to reagent level surface Dummy volume 2 types Dummy 1:Set volume/16+10 l(default)Dummy 2:Set volume/32+10 l Pipetting modes 1)Standard:Discharges set volume into reaction cell.2)Concentrate:Discharges
18、 concentrated reagent together with water.Reagent identification Identification through barcode label attached to reagent bottle Bottle freely settable Barcode reader incorporated in instrument(equipped in standard)Display of residual reagent volume Possible in pulse count system with electrostatic
19、type liquid level sensor Reagent control Positive ID,validity control and auto calibration possible through reagent barcode label Probe washing Washing of probe inside and outside with deionized water Program for washing with detergent settable 1.2.4 Reaction Unit Item Details Reaction disk Flatbed
20、disk,160 cells,1/4 turn+1 pitch every 4.5 s Reaction cell Material:Special plastic Shape:4.5 x 5 rectangular shape(optical path length 5 mm)Use:Semi-disposable Incubation bath Temperature-controlled water circulation system Display of temperature:Successive digital display on CRT Mixing system Stirr
21、ing with stirrers 1 and 2 driven independently Stirring speed:2500 pps,1300 pps(to be selected for each test using service ID)Stirring immediately after addition of R1,R2,R3 and R4 reagent(within 2 s)Cell rinsing Rinsing after completion of reaction Washing with detergent(twice:each with acid and al
22、kaline detergents,selectable for each test)Volume of each bottle:2 l Rinsing with water(4 or 5 times,including cell blank water)1-71.2.5 Measurement Unit(Photometer)Item Details Photometer system Multi-wavelength after-diffraction photometer Wavelength 12 wavelengths fixed 340,405,450,480,505,546,57
23、0,600,660,700,750,800 nm Light source Halogen tungsten lamp Spectral element Stigmatic concave grating Detector Silicon photodiode Photometric system Direct measurement of reaction cell,single wavelength or double wavelength simultaneous measurement Cell blank correction Correction with stopped cell
24、 blank(12 wavelengths)or passed cell blank(2 wavelengths)executed for each cell Optical path length 5 mm Minimum volume required for photometry 120 l 1.2.6 Measurement Unit(ISE Option)Item Details Electrode Liquid film type ion selective electrode,flow-through type Reference electrode Liquid film ty
25、pe ion selective electrode,flow-through type Liquid junction system Liquid-liquid junction,1 mol/1 KCL used Measuring temperature 33-37C,2C during measurement Measurement system Dilution(indirect)measurement Dilution rate 1/31(exclusive diluent used)Measurement cycle 18 s/sample(9 s for sample,9 s f
26、or internal standard)Reagent volume Diluent 450 l Internal standard 600 l(washing)+450 l(analysis)Reference solution 65 l Bottle capacity Diluent,internal standard:2 l each Reference solution 0.5 l Reagent remaining volume Count-down 1-81.2.7 Calculation Unit Item Details Type of multi-level analyti
27、cal curve Linear regression,Isozyme 3-parameter Log-Logit 4-parameter Log-Logit 5-parameter Log-Logit Exponential,Spline(up to 6 levels per test for standard)Analytical curve setting system Any of the following selectable by keyed-in request or automatic calibration algorithm 1)1-point calibration(r
28、eagent blank correction)2)1-point calibration(span correction)3)2-point calibration 4)Full calibration Accuracy control Control serum:Up to 10 types can be set Same-day variation of control serum statistically calculated and displayed in graph Daily variation of control serum statistically calculate
29、d and X-R control diagram displayed Altirule,real-time QC and double-value diagram displayed Above graph display printed Rerun processing Automatic rerun by rerun algorithm possible(possible in decreased volume,same volume and increased volume)Monitoring functions Graphic display of reaction time co
30、urse(routine and stat:10,000 tests,control:5000 tests,standard:1000 tests stored),graphic display of multi-level analytical curve,graphic display of calibration results(for foregoing 30 calibrations)Reagent remaining volume graph display Operation data control display Test-to-test calculation Compen
31、sation item(8 channels),calculation item(8 channels)Arithmetic operations freely combinable for both Printing functions Analytical results(monitoring format,reporting format),various worksheets and lists outputtable.Graphic printout possible.Online input/output Real-time and batch bi-directional com
32、munications Data storage Routine and stat samples:10,000(also with rerun results)Control 50 samples x 10 types Report preparation functions Entered patient attribute,normal values by age and sex,blood collecting time,etc.can be output together with analytical results as a report Statistical calculat
33、ion Reproducibility and correlation of analytical results calculable 1-91.2.8 Installation Conditions Item Details Power supply 100 V AC 10%,50/60 Hz Power capacity:2 kVA Grounding:C type Water supply/drain Supply of deionized water(RO type):approx.50 l/hr Input water pressure:49 to 343 kPa Drain op
34、ening diameter:at least 50 mm,height:100 mm or less Ambient temperature 15 to 32C(variation during measurement should be kept within 2C)Ambient humidity 45 to 85%RH(no condensation)Dimensions and weight Analytical unit:1,448(W)x 783(D)x 1,230(H)mm,and approx.400 kg Control unit:CRT 355(W)x 370(D)x 3
35、75(H)mm PC 430(W)x 430(D)x 130(H)mm Keyboard 460(W)x 170(D)x 60(H)mm Mouse 60(W)x 130(D)x 30(H)mm Approx.50 kg 1.2.9 Options Item Details ISE unit Na/K/CI 3 tests,200 samples/hr max.Sample ID unit Barcode reader using laser(13 digits)Chapter 2 Troubleshooting 2.1 Alarm Trace.2-1 2.1.1 Details of dai
36、ly alarm trace.2-1 2.1.2 Details of cumulative alarm trace.2-2 2.1.3 Retry code table.2-3 2.1.4 Key code table.2-5 2.1.5 Equipment status code table.2-6 2.1.6 Specifications concerning daily alarm trace for sample/reagent shortage alarm.2-8 2.2 Data Alarm.2-10 2.2.1 Data alarm registration flow.2-10
37、 2.2.2 List of data alarms.2-11 2.2.3 Relationship between data alarms and rerun TS requests.2-28 2.3 Analyzer Communication Trace.2-30 2.4 Host Communication Trace.2-31 2.5 Troubleshooting with Blue Screen.2-32 2.6 Dr.Watson Error.2-35 2.7 Troubleshooting for Key Mis-Operation.2-36 2.7.1 Mis-operat
38、ion until HP screen appears.2-36 2.7.2 Mis-operation after HP screen appears.2-36 2.7.3 Boot Devices screen.2-38 2.7.4 Boot on LAN screen.2-38 2.7.5 Mis-operation during booting of Windows NT.2-38 2.7.6 VGA mode.2-39 2.8 Alarm Code Table.2-40 2.9 Troubleshooting for Fault in Intra-Equipment Communic
39、ation.2-115 2.9.1 Location of created file.2-115 2.9.2 Details of trace.2-115 2.9.3 Collection of data.2-116 2.10 Power-Up with Fuses Blown.2-116 2-1 2.1 Alarm Trace 2.1.1 Details of daily alarm trace The alarm/retry/key data of one cycle will be printed(up to 2000 cycles).DAILY ALARM TRACE 00/06/23
40、 10:15 06/23 09:15 7 10 A 1-020-030-001 1-100-065-002 2-021-031-110 2-024-035-123 X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX R X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX K XXX-XXX-XXX 06/23 08:30 6 9 A X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-
41、XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX R X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX 06/23 08:30 7 XXX A X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX Number of occurrences(1-999)A:Alarm K:Key code R:Retry Instrument stat
42、us Alarm/retry/key occurred In case of alarm(A)(up to 10):In order of division,sub-division and time of occurrence In case of retry(R)(up to 10):In order of retry code,number of retries and time of occurrence In case of key(K)(1):In order of key operation code,number of key operations and time of oc
43、currence CPU number(1:control unit,2:analytical unit)Date/time of occurrence 2-2 2.1.2 Details of cumulative alarm trace The alarm/retry/key data for one day will be printed(up to 256 days).CUMULATIVE ALARM TRACE 00/06/23 10:15 00/06/20 09:10 15:30 A 1-020-030-001 1-100-065-002 2-021-031-110 2-024-0
44、35-123 X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX R X-XXX-XXX X-XXX-XXX X-XXX-XXX X-XXX-XXX X-XXX-XXX X-XXX-XXX X-XXX-XXX X-XXX-XXX K XXX-XXX-XXX XXX-XXX-XXX XXX-XXX-XXX XXX-X
45、XX-XXX 00/06/10 10:10 16:00 A X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX R X-XXX-XXX X-XXX-XXX X-XXX-XXX X-XXX-XXX 00/06/01 08:30 15:20 A X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX X-XXX-XXX-XXX CPU number(1:control unit,2:analytical
46、unit)Date of occurrence Time power is turned on Time alarm finally occurs Alarm/retry/key occurred In case of alarm(A)(up to 40):In order of division,sub-division and time of occurrence In case of retry(R)(up to 24):In order of retry code and number of retries In case of key(K)(up to 16):In order of
47、 key operation code,number of key operations and time of occurrence A:Alarm K:Key code R:Retry 2.1.3 Retry code tableCodeDetailsAllowable numberRemarks1Disconnection of alarm fuse1/50ms212 V for lamp1/4.5secMonitoring is interrupted when lamp is off(when initializing and replacing water,orduring sle
48、ep)315 V on CPU rack1/50ms4-15 V on CPU rack1/50ms55 V on HMCONT1 board1/50ms65 V on HMCONT2 board1/50ms75 V on HMCONT3 board1/50ms85 V on ADC1 board1/50ms95 V on ADC2 board1/50ms105 V on BCRCONT board1/50ms115 V on DI board1/50ms1224 V on DO1 board1/50msNot monitored during sleep1324 V on DO2 board
49、1/50msNot monitored during sleep14Liquid remaining in vacuum tank1/4.5sec15Vacuum faulty1/4.5secMonitoring is interrupted for 10 secondsafter vacuum pump is turned on.16Waste solution tank1/4.5sec17Shortage of water in incubation bath100/4.5secStandby,Operation,Sampling stop18Shortage of deionized w
50、ater20/4.5secMonitoring is interrupted duringinitialization,exchange of water,wakeup.19Deionized water faulty1/4.5secMonitoring is interrupted duringinitialization,exchange of water,wakeup.20Temperature inside equipment1/4.5secCPU rack,transformer,AC power supply212223Voltage drop 5 V in power resto