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1、最大限度地展示您的研究成果最大限度地展示您的研究成果 英语医学论文写作实例分析英语医学论文写作实例分析张科宏博士张科宏博士长青藤编辑总裁长青藤编辑总裁同济大学生命科学院兼职教授同济大学生命科学院兼职教授Tel:021-51370992论文核心内容论文核心内容1）标题）标题2）摘要）摘要3）正文）正文E-mail:;Tel:02151370992论文核心内容论文核心内容1）标题）标题 目的：在第一时刻抓住读者审稿人的目光目的：在第一时刻抓住读者审稿人的目光E-mail:;Tel:02151370992论文核心内容论文核心内容1）标题）标题 目的：在第一时刻抓住读者审稿人的目光目的：在第一时刻抓住
2、读者审稿人的目光 技巧：把主要研究结果技巧：把主要研究结果“装入装入”标题标题E-mail:;Tel:02151370992论文核心内容论文核心内容1）标题）标题2）摘要）摘要 目的：吸引读者审稿人引入正文目的：吸引读者审稿人引入正文E-mail:;Tel:02151370992论文核心内容论文核心内容1）标题）标题2）摘要）摘要 目的：吸引读者审稿人引入正文目的：吸引读者审稿人引入正文 技巧：给出一个完整的技巧：给出一个完整的“故事梗概故事梗概”E-mail:;Tel:02151370992论文核心内容论文核心内容1）标题）标题2）摘要）摘要3）正文）正文 目的：将一个完整的目的：将一个完整
3、的“故事故事”呈现给读者呈现给读者E-mail:;Tel:02151370992论文核心内容论文核心内容1）标题）标题2）摘要）摘要3）正文）正文 目的：将一个完整的目的：将一个完整的“故事故事”呈现给读者呈现给读者 技巧：换位思维，撰写稿件时以读者为中心技巧：换位思维，撰写稿件时以读者为中心E-mail:;Tel:02151370992常见问题常见问题E-mail:;Tel:02151370992The current study is the randomized,placebo-controlled clinical trial.E-mail:;Tel:02151370992E-mail
4、:;Tel:02151370992The current study is the randomized,placebo-controlled clinical trial.E-mail:;Tel:02151370992The current study is a randomized,placebo-controlled clinical trial.The current study is the randomized,placebo-controlled clinical trial.E-mail:;Tel:02151370992冠词运用不当冠词运用不当E-mail:;Tel:02151
5、370992International Journal of Radiation Oncology Biology Physics,67:888-896,2007Due to the complex molecular pathogenesis of glioblastoma multiforme,therapeutic strategies are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growt
6、h such as cyclooxygenase-2(COX-2),a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.E-mail:;Tel:02151370992International Journal of Radiation Oncology Biology Physics,67:888-896,2007Due to the complex molecular pathogenesis of glioblastoma multiforme,therapeutic strategies
7、 are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2(COX-2),a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.E-mail:;Tel:02151370992International Journal of Radiation Onc
8、ology Biology Physics,67:888-896,2007Due to the complex molecular pathogenesis of glioblastoma multiforme,therapeutic strategies are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2(COX-2),a rate-lim
9、iting enzyme in conversion of arachidonic acid into prostaglandins.E-mail:;Tel:02151370992International Journal of Radiation Oncology Biology Physics,67:888-896,2007Due to the complex molecular pathogenesis of glioblastoma multiforme,therapeutic strategies are evolving from cytotoxic therapies to mo
10、lecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2(COX-2),a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.E-mail:;Tel:02151370992International Journal of Radiation Oncology Biology Physics,67:888-896,2007Due to
11、the complex molecular pathogenesis of glioblastoma multiforme,therapeutic strategies are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2(COX-2),a rate-limiting enzyme in conversion of arachidonic ac
12、id into prostaglandins.E-mail:;Tel:02151370992理解困难的超长复合句理解困难的超长复合句E-mail:;Tel:02151370992The frequency of the 03 allele of the DRB1 gene in the hepatitis B and hepatitis C groups was significantly higher than the controls.However,the allele frequency of DRB1-15 in the chronic hepatitis B/C groups wa
13、s lower than the controls.E-mail:;Tel:02151370992The house is big enough.（）（）I dont like its location.房子够大，房子够大，（）（）我不喜欢它的地点。我不喜欢它的地点。E-mail:;Tel:02151370992The earth has relatively little iron.()this newly discovered planet contains more iron than any other element.地球含铁量很小。地球含铁量很小。（）（）这个新发现的行星含铁这个新
14、发现的行星含铁高于任何其他元素。高于任何其他元素。E-mail:;Tel:02151370992The earth has relatively little iron.This newly discovered planet,in contrast,contains more iron than any other element.地球含铁量很小。这个新发现的行星地球含铁量很小。这个新发现的行星则相反则相反，含铁高于任何其他元素。含铁高于任何其他元素。E-mail:;Tel:02151370992The frequency of the 03 allele of the DRB1 gene
15、in the hepatitis B and hepatitis C groups were significantly higher than the controls.However,the allele frequencies of DRB1-15 in the chronic hepatitis B/C groups were lower than the controls.E-mail:;Tel:02151370992The frequency of the 03 allele of the DRB1 gene in the hepatitis B and hepatitis C g
16、roups were significantly higher than the controls.However,the allele frequencies of DRB1-15 in the chronic hepatitis B/C groups were lower than the controls.The allele frequency of DRB1-15 in the chronic hepatitis B/C groups,in contrast,was lower than the controls.E-mail:;Tel:02151370992科学逻辑表述不正确科学逻
17、辑表述不正确E-mail:;Tel:02151370992International Journal of Radiation Oncology Biology Physics,67:888-896,2007Due to the complex molecular pathogenesis of glioblastoma multiforme,therapeutic strategies are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades t
18、hat promote tumor growth such as cyclooxygenase-2(COX-2),a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.E-mail:;Tel:02151370992Despite of the complex molecular pathogenesis of glioblastoma multiforme,therapeutic strategy are evolving from cytotoxic therapies to molecula
19、r approaches.Activation of cyclooxygenase-2(COX-2),the rate-limiting enzyme in prostaglandin biosynthesis,promotes tumor growth,and therefore represents a promising target for intervention.Due to the complex molecular pathogenesis of glioblastoma multiforme,therapeutic strategies are evolving from c
20、ytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2(COX-2),a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.E-mail:;Tel:02151370992Recent evidence suggests that interleukin-17 may play a pu
21、tative role in innate immunity.E-mail:;Tel:02151370992Recent evidence suggests that interleukin-17 may play a putative role in innate immunity.E-mail:;Tel:02151370992Recent evidence suggests that interleukin-17 may play a putative role in innate immunity.Interleukin-17 has recently been implicated i
22、n innate immunity.E-mail:;Tel:02151370992概念表述重复概念表述重复E-mail:;Tel:02151370992ResultsIn order to examine the effects of sitagliptin on glucose level,diabetic rats were treated with various doses of sitagliptin.The blood glucose level was significantly different between the H and M groups compared with
23、 the C group.The L group was not statistically different from the C group.E-mail:;Tel:02151370992ResultsIn order to examine the effects of sitagliptin on glucose level,diabetic rats were treated with various doses of sitagliptin.The blood glucose level was significantly different between the H and M
24、 groups compared with the C group.The L group was not statistically different from the C group.E-mail:;Tel:02151370992ResultsIn order to examine the effects of sitagliptin on glucose level,diabetic rats were treated with various doses of sitagliptin.The blood glucose level was significantly differen
25、t between the H and M groups compared with the C group.The L group was not statistically different from the C group.E-mail:;Tel:02151370992ResultsIn order to examine the effects of sitagliptin on glucose level,diabetic rats were treated with various doses of sitagliptin.The blood glucose level was s
26、ignificantly different between the H and M groups compared with the C group.The L group was not statistically different from the C group.E-mail:;Tel:02151370992ResultsIn order to examine the effects of sitagliptin on glucose level,diabetic rats were treated with various doses of sitagliptin.The bloo
27、d glucose level was significantly different between the H and M groups compared with the C group.The L group was not statistically different from the C group.ResultsSitagliptin significantly decreased blood glucose concentration in diabetic rats at 10 and 20 mg/kg/d,but not at a lower dose of 5 mg/k
28、g/d.E-mail:;Tel:02151370992概念表述不到位不具体概念表述不到位不具体描述描述“不友好不友好”（干预分组缩写）（干预分组缩写）E-mail:;Tel:02151370992An anti-ErbB2 antibody reverses resistance of breast cancer cells to paclitaxel by down-regulating Akt/NF BE-mail:;Tel:02151370992Paclitaxel is the drug of choice with significant anti-tumor activity to
29、wards breast cancer,ovarian cancer,cervical cancer,among others.However,the success of paclitaxel in the treatment of advanced or drug-resistant breast cancers is limited because of largely associated highly non-specific cytotoxicity.Furthermore,there is no specific treatment for metastasis that fol
30、lows surgery,radiotherapy,and chemotherapy.Tumors tend to acquire resistance to chemotherapeutic agents,including paclitaxel.Akt is suggested to be involved in chemoresistance.E-mail:;Tel:02151370992An anti-ErbB2 antibody reverses resistance of breast cancer cells to paclitaxel by down-regulating Ak
31、t/NF BE-mail:;Tel:02151370992An anti-ErbB2 antibody reverses resistance of breast cancer cells to paclitaxel by down-regulating Akt/NF B 1）paclitaxel 是治疗乳腺癌的首选药是治疗乳腺癌的首选药 2）癌细胞长期暴露于）癌细胞长期暴露于 paclitaxel 产生耐药产生耐药 3）乳腺癌耐药的主要机理）乳腺癌耐药的主要机理 4）ErbB2 Akt/NF B 通路和耐药的关系通路和耐药的关系E-mail:;Tel:02151370992Paclitaxe
32、l is the drug of choice with significant anti-tumor activity towards breast cancer,ovarian cancer,cervical cancer,among others.However,the success of paclitaxel in the treatment of advanced or drug-resistant breast cancers is limited because of largely associated highly non-specific cytotoxicity.Fur
33、thermore,there is no specific treatment for metastasis that follows surgery,radiotherapy,and chemotherapy.Tumors tend to acquire resistance to chemotherapeutic agents,including paclitaxel.Akt is suggested to be involved in chemoresistance.E-mail:;Tel:02151370992概念层次多余不合理概念层次多余不合理E-mail:;Tel:02151370
34、992Wang et al.,Neuroscience Letters 382:236-241,2005Acupuncture,a pearl in the Traditional Chinese Medicine,has been shown to bring about functional recovery after spinal cord injury,it has been widely used by doctors and favorably received by patients.E-mail:;Tel:02151370992Wang et al.,Neuroscience
35、 Letters 382:236-241,2005Acupuncture,a pearl in the Traditional Chinese Medicine,has been shown to bring about functional recovery after spinal cord injury,it has been widely used by doctors and favorably received by patients.E-mail:;Tel:02151370992南宋末年，金兵大举入侵中原，朝廷昏聩无力，南宋末年，金兵大举入侵中原，朝廷昏聩无力，百姓生灵涂炭。话说
36、嵩山脚百姓生灵涂炭。话说嵩山脚下一对杨姓夫妇，年过半百，膝下尚无子嗣。下一对杨姓夫妇，年过半百，膝下尚无子嗣。E-mail:;Tel:02151370992海上起了风暴，老约翰还是开着破船驶离了港湾。海上起了风暴，老约翰还是开着破船驶离了港湾。南宋末年，金兵大举入侵中原，朝廷昏聩无力，南宋末年，金兵大举入侵中原，朝廷昏聩无力，百姓生灵涂炭。话说嵩山脚百姓生灵涂炭。话说嵩山脚下一对杨姓夫妇，年过半百，膝下尚无子嗣。下一对杨姓夫妇，年过半百，膝下尚无子嗣。E-mail:;Tel:02151370992Acupuncture,a pearl in the Traditional Chinese Me
37、dicine,has been shown to bring about functional recovery after spinal cord injury,it has been widely used by doctors and favorably received by patients.Acupuncture expedites the functional recovery after spinal cord injury.E-mail:;Tel:02151370992文化差异文化差异E-mail:;Tel:02151370992AbstractThe present stu
38、dy examined the role of dopamine D4 receptor on prepulse inhibition in rats.Gating deficit was induced pharmacologically using ketamine.Rats then received daily treatment with the D4-selective antagonist CP-293,019 vs.saline.E-mail:;Tel:02151370992AbstractAbberant information processing(e.g.,gating
39、deficit)is the basis of many cognitive deficits in schizophrenia.Since dopamine D4 receptor is elevated in the brain of schizophrenia patients,we examined whether D4 receptor antagonism could alleviate gating deficit in a rat model.Prepulse inhibition was disrupted.E-mail:;Tel:02151370992摘要缺乏摘要缺乏“故事
40、故事”情节情节 E-mail:;Tel:02151370992Effects of nifedipine on blood pressure in patients with primary hypertension vs.healthy controlsE-mail:;Tel:02151370992Effects of nifedipine on blood pressure in patients with primary hypertension vs.healthy controlsNifedipine decreases blood pressure in patients with
41、 primary hypertension but not in healthy controlsE-mail:;Tel:02151370992标题信息量太小标题信息量太小E-mail:;Tel:02151370992The study is potentially interesting and may in principle be suitable for this Journal.However,the paper is poorly presented and has little compliance with the format of our Journal.I have ha
42、d a policy of greatly encouraging and accepting manuscripts from China,but the current widespread attitude of sending over manuscripts that are not properly prepared is being counterproductive,and it is not right that you should expect that other scientists should do the work of putting these papers
43、 right on your behalf.E-mail:;Tel:02151370992不够认真不够认真E-mail:;Tel:02151370992Consulting Editors:自由作家自由作家 Jesse Potash,PhD 曾任曾任 Nature Methods 杂志编辑杂志编辑哈佛大学医学院哈佛大学医学院 Ross Baldessarini,MD 教授教授西佛吉尼亚州大学医学西佛吉尼亚州大学医学院院 James ODonnell,PhD 教授教授Jackson Laboratory Leslie Goodwin,PhD 高级科学家高级科学家长青藤编辑部分成员Deputy Editors:布布朗朗大学大学 Teige Sheehan,PhD 前前助理教授助理教授 自由作家自由作家 Anthony White,PhD 美国心脏协会前高级医学编辑美国心脏协会前高级医学编辑 波士顿临床试验中心波士顿临床试验中心 Matthew Brier,MD 研究员研究员 罗切斯特大学罗切斯特大学 Christina Lilliehook,PhD 前前助理教授助理教授E-mail:;Tel:02151370992