《免疫学课程教学大纲.pdf》由会员分享，可在线阅读，更多相关《免疫学课程教学大纲.pdf（4页珍藏版）》请在taowenge.com淘文阁网|工程机械CAD图纸|机械工程制图|CAD装配图下载|SolidWorks_CaTia_CAD_UG_PROE_设计图分享下载上搜索。
1、免疫学免疫学课程教学大纲课程教学大纲Course Outline课程基本信息（Course Information）课程代码（Course Code）*课程名称（Course Title）*课程性质（Course Type）授课对象（Target Audience）*授课语言(Language of Instruction)*开课院系（School）先修课程（Prerequisite）授课教师（Instructor）苏冰课程网址(Course Webpage)本科二年级/三年级双语（汉语+英语）致远学院MS310*学时（Credit Hours）64*学分（Credits）4.0（中文）免疫学
2、（英文）Principle of Immunobiology选修课本课程是介绍现代免疫生物学基本原理的半学年课程。主要将介绍免疫系统的生成，发育和调控及其在人类传染疾病，免疫疾病，炎症及肿瘤中的作用。本课程的目的不仅在于阐明上述免疫学的重要基本原理，同时也将讨论其发展过程和一*课程简介（Description）些主要的实验手段。并介绍其同其它生命学科的密切相关性，和其研究的方法。本课程不仅适用于生命科学和医学的学生，同时也适合那些有意愿了解基本免疫学生物学知识的生物工程学专业的学生。This course is a half-year course which introduces the b
3、asic principles of modernimmunobiology.It will focus on the generation,development and regulation of theimmune system and its function in human epidemics,immunological diseases,inflammation and tumor.The aim of this course is not only to elucidate these keyprinciples of immunology,but also to discus
4、s its history of discovery and some major*课程简介（Description）experimental techniques.The course will also introduce the close relationship ofimmunology to the other sub disciplines of life science and research methods.Thiscourse is not only suitable for the students who majors in life science or medic
5、alscience,but is also good for the students who major in biomedical engineering whowant to pick up some basic knowledge in immunology.课程教学大纲（course syllabus）1.掌握免疫系统组成和功能。Introduction to the immune system.2认识固有免疫系统的识别，理解炎症和感染、急性时相反应，讨论固有免疫细胞的免疫学功能。Describeinnate immune recognition.UnderstandInflamma
6、tion,infection andacute phase responses.Discussimmunological Function of innate immune cells,suchas monocyte,macropahge and DC,etc.3认识 T,B淋巴细胞的发育，了解淋巴细胞抗原受体基因结构和V(D)J 重排。Describe the development of T and B cells.Recognize the TCR and BCR genestructures and V(D)J rearrangement.4.认识 T 细胞抗原受体及其对抗原的识别，了
7、解 T 淋巴细胞的成熟和迁移；掌握 T 细胞激活和 T 细胞亚群的分化及 T 细胞的功能。DescribeTCellreceptorandantigenrecognition.UnderstandT lymphocyte maturation and migration in the Lymphoid Organs.DescribeTcellactivation,differentiation and the function of effector T cells.*学习目标(LearningOutcomes)5.认识 B 细胞介导的免疫应答和生发中心的反应，理解 Ig 类别转换、体细胞高频
8、突变和抗体亲和力成熟，认识免疫球蛋白分子结构、分类和功能。Recognize B cell mediated immune response and germinal center reacyion.Understand Ig class switch,somatic hypermutation and affinity maturation.Describethe structure,classification and function of immunoglobulin.6认识和比较B和T细胞受体信号转导,认识细胞因子的作用和信号转导。Recognize and compare the
9、difference of BCR and TCR signal transduction.Recognizethe cytokines and signaling pathways.7.认识MHC 基因和结构,比较 MHC I 类和 II 类分子抗原提呈的区别。Describe MHC gene and structure.Compare the difference of MHC I molecule andMHC II molecule presenting antigen.8.认识免疫进化，了解固有免疫应答对后天性免疫应答的控制和激发以及免疫记忆，了解疫苗的功能。Recognize i
10、mmune evolution.Understand the induction of the adaptive immunityby innate immune response and immunological memory.Describe the function ofvaccine.9.认识黏膜免疫的组成和功能。Recognize mucosal immune system and mucosal immunity.10.认识抗感染免疫的具体机制。Recognize immune response to infection(virus,fungi,bacteria).11.认识肿瘤
11、免疫逃逸及机体抗肿瘤免疫。Understand the immunological principles of tumor immune escape,anti-tumorimmunity.12.理解移植排斥的免疫学原理。Understand the immunological principles of transplant rejection.13.认识免疫缺陷，认识自身免疫病的病理损伤机制和相关治疗。Recognize immunodeficiency.Understand pathological damage mechanism andtherapeutic principle of
12、 autoimmune disease(such as SLE、RA、Diabetes etc.).教学内容Introductionto theImmuneSystemInnateImmuneRecognitionandInflammationDevelopmentofLymphocytesAdaptiveImmuneReceptor andAntigenRecognitionTCR and BCRsignaltransductionGenerationandRegulation ofAdaptiveImmunityMHC andAntigenPresentation学时教学方式作业及要求基本
13、要求考查方式4课堂教学预复习4课堂教学预复习6课堂教学预复习*教学内容、进度安排及要求(Class Schedule&Requirements)4课堂教学预复习4课堂教学预复习4课堂教学预复习8课堂教学预复习GenerationandRegulation ofAdaptiveImmunityTheRelationshipbetweenInnateImmunity andAdaptiveImmunity,ImmunologicalMemoryThe ImmuneSystem inHealth andDisease2课堂教学预复习10课堂教学预复习10课堂教学预复习*考核方式(Grading)*教材或参考资料(Textbooks&OtherMaterials)其它（More）备注（Notes）备注说明：考试，中期考试和期末考试各占总成绩的50%ImmunoBiology,by Kenneth Murphy(Janeways ImmunoBiology),Garland Science;8th Edition(July 25,2011)1带*内容为必填项。2课程简介字数为 300-500 字；课程大纲以表述清楚教学安排为宜，字数不限。