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1、Malnutrition in Patients With Cancer:Comparison of Perceptions by Patients,Relatives,and PhysiciansResults of the NutriCancer2012 StudyJournal of Journal of Parenteral and Parenteral and Enteral NutritionEnteral NutritionIF：3.517Publication:Jan 20171 研究背景及目的01研究结果03研究对象及方法02讨论及总结04THE MAIN CONTENTS2
2、2023/6/81第部分研究背景及目的32023/6/8研究背景及目的01Malnutrition increases the risk of treatment toxicity and impairs outcomes of patients with cancer.Early nutrition interventions are recommended in properly identified patients for improving treatment tolerance and patient survival.Underestimation of malnutrition
3、 remains a significant issue since early recognition of malnutrition may allow for early optimization of nutrition interventions to support patients during treatment.Patient self-screening for malnutrition has been reported as feasible in cancer,and relatives may also provide external information on
4、 nutrition.42023/6/8研究背景及目的01questions:Whether patients with cancer and/or their relatives are aware of malnutrition and could improve the efficacy of nutri-tion interventions is unclear.However,the subjective awareness of malnutrition by the patients,their relat-ives,and physicians has not yet been
5、 assessed or compared.52023/6/8研究背景及目的01ObjectiveTo compare the validated definition of malnutrition with the perceptions of nutrition status by patients,relatives,and physicians.To find out the risk factors of malnutrition.62023/6/82第部分研究方法及对象72023/6/802研究方法及对象MethodsThe NutriCancer2012 multicentri
6、c cross-sectional survey was conducted on 1 predefined day.The survey was conducted in 283 departments of private or public hospitals in 36 cities in France on October 9,2012,and included 2197 patients.Each included patient had to complete a questionnaire.The att-ending physician on the day of the v
7、isit was included,as well as the closest relative,who also received questionnaires to com-plete.82023/6/802研究方法及对象Inclusion criteriapatients diagnosed with cancer,aged 18 years,and willing to complete a questionnaire.Malnutrition was identified as follows:weight loss 5%within 1 month or 10%within 6
8、months,a body mass index(BMI)18.5 kg/m2 in patients aged 70 years or 21 kg/m2 in patients aged 70 years,albu-minemia(when available)35 g/L in patients aged 70 years.92023/6/83第部分研究结果102023/6/8研究结果03112023/6/8研究结果03Malnutrition prevalence and statistical analysis:Overall,826 patients were malnourishe
9、d(39%;95%confidence interval CI,3741),with a higher pre-valence in patients with liver and pancreatic cancers 122023/6/8研究结果03Malnutrition was identified in 40%,40%,and 31%of patientsin initial evolution,relapse,or remission,respectively,and 27%of patients with local disease stage.132023/6/8研究结果03 P
10、revalence of malnutrition was 39%.Physicians overestimated malnutrition(44%),whereas patients and relatives underes-timated it(24%and 25%,respe-ctively,P .001).142023/6/8研究结果03According to quest-ionnaires,57%of patients and 61%of relatives reported a lower food intake,m-ainly because of GIsymptoms.1
11、52023/6/8研究结果03Nutrition int-erventions were recalled and were m-ore frequent in malnouri-shed patients162023/6/84第部分讨论及总结172023/6/8讨论及总结04This study confirmed the high prevalence of malnutrition(39%)in patients with cancer.The percentage obtained is slightly higher than the 30.9%found in a previous
12、 study by Pressoir et al7 and lower than the 43.5%and 52%reported by Nourissat et al8 and Segura et al,9 respectively.One explanation could be the different proportions of pa-tients with GI locations:32%in our study compared with 17%and 34%in the studies by Pressoir et al7 and Nourissat et al,8 resp
13、ectively,while in the study by Segura et al,9 the proportion of patients with pancreatic and lung cancers was higher.01182023/6/8讨论及总结0402Patients and relatives underestimated malnutrition while physicians overestimated it,indicating a low awareness of patients and relatives regarding malnutrition in cancer.Further studies are needed to improve the awareness of mal-nutrition in patients and their relatives as well as the efficacy of nutrition interventions.192023/6/8讨论及总结04请老师同学指正批评时间：2017.3.15Thanks for your attention202023/6/8