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1、七年制医学课件耳鼻喉七年制医学课件耳鼻喉4 4喉癌喉癌2.Etiology,unclear(1)smoking(2)drinking(3)air containtment(4)virus infection HPV(5)hormone(6)pre-malignant leisions(癌前病变)papilloma of the larynx(喉乳头状瘤)leukoplakia of the larynx(喉白班病)正正 常常 喉喉 部部Multiple papillomas of the larynxPapillomatosis of the larynxPapilloma of the la
2、rynxPapilloma of the larynx and tracheaLeukoplakia with dysplasia of the vocal cords Chronic parakeratotic laryngitis3.Pathology 93%99%squamous cell carcinoma better differentiated(I-II)4.Clinical symptoms and signs supraglottic carcinoma 声门上型癌 glottic carcinoma 声门型癌 subglottic carcinoma 声门下型癌(1)sup
3、raglottic carcinomaA.early stage:(atypical)haemoptysis(痰中带血)Sore throat（喉痛）Irritating cough(刺激性咳嗽)B.later stage:Hoarsness（声嘶）Dyspnea（呼吸困难）C.easily lymph node matastases(淋巴结转移)Carcinoma of the epiglottisAdvanced squamous cell carcinoma of the larynx(2)glottic carcinoma A.early stage hoarsness B.later
4、 stage dyspnea(呼吸困难)C.difficulty matastases(3)sybglottic carcinoma same as supraglottic carcinomaCarcinoma in situ of the left vocal cordCarcinoma of the anterior glottisSquamous cell carcinoma of thearyepiglottic fold and piriform sinus5.Diaglosis biopsy（活检）（活检）x-ray、CT-scan、MRI6.Treatment(1)operation(手术手术)partial laryngectomy（部分喉切除术）（部分喉切除术）total laryngectomy（全喉切除术）（全喉切除术）(2)radiatherapy（放射治疗）（放射治疗）(3)chemotherapy（化学治疗）（化学治疗）结束语结束语谢谢大家聆听！谢谢大家聆听！20