《常见癌症诊断常见癌症诊断 (4).pdf》由会员分享，可在线阅读，更多相关《常见癌症诊断常见癌症诊断 (4).pdf（30页珍藏版）》请在taowenge.com淘文阁网|工程机械CAD图纸|机械工程制图|CAD装配图下载|SolidWorks_CaTia_CAD_UG_PROE_设计图分享下载上搜索。
1、?ss?yy?)&?ww?&?、?、?+&?、?,&?pp?-&?.&?yy?/&?ii?ll?mm?yy?ww?+?ww?ww?)?(?(?(?(?)?nn?nn?C?4C?4?nn?/-?(/-?(?nn?nn?-0-0?nn?)-)-?ww?nn1 1?nn1 1?-?-?(?(?),),?(?)()(,?(?)()(,?llNGSmm?nn?(0?(0?nn?DNA?nn?zz?(1?(1?nn?hh?nn?ii?llTCGAmm?llPCAWGmm?nn?uu?nn?ii?nn?iiMILESTONE 7?First cancer whole-genome sequenceMILES
2、TONE 11?Clonal diversity of tumor cells as a basis for cancer progression and treatment resistance)1/.)1/.?nn?ss?3 3?(?(?nn?nn?()?()?nn?zz?nn?yy?()?()?nn?nn?3 3?hh?ii?()?()?nn?()+?()+?nnEZH2?ss?nn?H3K27me3?zz?()/?()/?nn?H3K27me3?ss?ll?CDKN2Ammnn?nn?nn?、?()1?()1?nn?yy?nn?nn?yy?xx?iiss?iiMILESTONE 10?
3、Epigenetic drivers of tumor initiation and progression?%?nn?yy?ss?bb?ccnn?ww?ss?yy?ii?(?(?nn?)1)1?ii?nn?nn?nn?zz?nn?ss?bb?cc?ii?nn?xxnn?nn?ss?bb?ccnn?ii?nn?hh?nn?ii?nn?xx?ii?ss?nn?ss?ii?yy?(?(?(?()(?)&)&?yy?&?&?+&?,&,&?-&-&?.&.&?/&/&?0&0&?1&1&?zz?)(&)(&?)%?yy?yy?nncell-in-cell?yy?%?)&)&?&?&?+&+&?,&,
4、&?%?+%?)&)&?&?&?+&+&?pp?“?nn?nn?pp+%)?a?a?ppHomeostasisnn?nn?bb?nnuu?nn?dddddd?iicc%?)&)&?r?Q7?zz?yy?rr?zz?yy?nn?hh?nn?nn?nn?ii?pp)LS)LS+?g?)(g?)(1 1?e?)(LSe?)(LS+?g?)(g?)()?)?)(?)(+?+?g?g?)()(e?)(e?)(+?,?+?,?g?g?)(?,)(?,)()()?)?g?g?,(,(ss?)()()?)?rr40?)?)?nn?-?nnyy?)?-?-?yy?nn?yy?T T?nn?D?h?D?b?fo?D?,?+?t?eDh?L?y?w?H?u?enc?v?&?&?%?%?zz?“?+&?)?)?nn?(+?(+?+-+-?nn?).0).0?nn?