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1、精选学习资料 - - - - - - - - - 第四章 缩合反应练习题一、举例说明或说明以下人名反应；1. Mannich 反应 2. Strecker反应 3. Michael 反应 4. Knoevenagel反应 5. Perkin 反应 6. Stobbe反应 7. Wttig 反应 8. Darzens反应 9. Diels-Alder 反应 10. Aldol 缩合二、请选出以下反应的主产物；1.ClCH 2COOC 2H5t-BuOK O t-BuOHA.ClCHCOOC 2H5CHCOOC2H5B.ClCH 2COOCHCH2OOC2H5C.OHClCHCOOO CHCOOC
2、2H5CH2COOC2H5CHCH 2OOC2H5D.2.Cl+ CHO浓NaOD/D 2O A.CH2OD+COOHB.CH2OH+COONaC.CH2OD+COONaD.CH2ONa+COONa3.CH 32CCHCHOOH B.CH32CCHCH2 CHCCHCHOA.CH32CCHCH2 CH2 CCHCHOCH3OHCH3C.CH32CCHCH2 CH2 CCHCOOHD.CH32CCHCHCHCCHCHOCH3CH3O4.+O加热 O名师归纳总结 - - - - - - -第 1 页,共 9 页精选学习资料 - - - - - - - - - OOOO5.A.+ OB.OC.OD.
3、OOOOOOONaOEtCHONaEtOH6.A.HCHOB. HCOOEtC.HOOCCOOHD.CO2CH 3CH 2CO 2O CH 3CHOCH 3 CH 2 COOK,加热A.H3CCHOB.H3CCH 2COOHCH3OOHC.H3CCHCCOOHD.H3CCHCOOHCH 3CH 3O7.A.+CH2COOC 2H52C2H5ONa CCOOC2H52OB.CHCOOC2H52名师归纳总结 OOCOCH2COOC2H5第 2 页,共 9 页C.D.CHCOOC2H528. CH3CH2COOH Br2 C2H5OH红P H+ OHZn, 甲苯H3O+CHCOOC 2H5CH 3-
4、 - - - - - -精选学习资料 - - - - - - - - - A.CH3CH2COBrCH3CHCOOC2H5OCH2CH39.B.CH3CHCOOHCH3CHCOOC2H5OBrBrC.BrCH 2CH2COOHCH3CHCOOHOD.CH2CH3OCH3CH2CHOCH3CH2COOC2H5COCH 3+ HCHO +N HHCl 10.AOH2 CC H2N.HClBOHH2 CCH 3.HClCNCOH CC HN.HClDO H 2 C CCH 3.HClCHCHO 浓OH CHO + HCHOOH 稀A.CH2OHCH2OHCHOCH2OHCHOCH2OHB.CHOCO
5、OHC.CH2OHCOOHD.CH2OCHOCH2CH2OHCH2OHCOOHO11. Ph 3P=CH 2 CH 2I2 Zn过量O名师归纳总结 A.CH2B.CH2第 3 页,共 9 页C.CH2D.CH2CH2CH2OCH2- - - - - - -精选学习资料 - - - - - - - - - 12.OHH2 Na 2Cr2O7 稀 OH 加热Ni H2SO413.OHCOOHOHOBOHOOA.B.C.OHOOD.OHOOOCH 3CHCH 2CH2CH2COOHH+ OH加热AH2CCHCH 2CH 2CH 2COOHH 3CHCCHCH 2CH 2COOHCODOOCH3CHC
6、H 2CH 2CH 2CO CCH 2CH2CH2CHCH 3OOHOHCH 3OH14.A.CH3COCl AlCl 3 CH3OCH3OOHOHOOCCH3O CB.CC O15.A.OC.CH3OHCH 3D.OCH3CHCHOOOCOCCH3OHOD.C OCCH3COCH3CH3CHO + CH3CHO稀NaOHC H OOHB.OOOHC.COOCH3名师归纳总结 16.HCOClNH 3 Br2-NaOH 第 4 页,共 9 页H2C- - - - - - -精选学习资料 - - - - - - - - - A.CH3NH 2CH3B.CH3CH3HCONH 2HCONHBrHC
7、ONH 2HBrH2CH2CH2CH2C17.C.HCH3HCH22OCH3CH3CONH 2D.HCONH2HNH 2H2CH2CH2CH2COKOH ONNH18.O OHCH2BrOOOCH2OHA.B.OOHOOC.D.OCH2OHOCH2BrNHNKOOCOOEtC 2H5 ONa 稀NaOH-H 2 O H3 O+, 加热CH 3COOH/HA.OOOOHB.OOCOOEtOHOC.名师归纳总结 19.D.CHOOOO OHOOH第 5 页,共 9 页OO+ Ac 2OCH 3CO 2K- - - - - - -精选学习资料 - - - - - - - - - A.OCH2COOH
8、B.OCHCHCOOKC.HOOCH 2COCHOD.OCH2COOHCHOCHOO20.A.O+ ClCH 2COOEtt-BuOK t-BuOH OCOOEtHOClCOOEtCOOEtCOOEtB.C.D.21.A.N H OH2CC HCCH 3 NaOAc 加热H2OHCH3CH3CH3NOOOHOCH2CH2CCH3B.CH3CH3 OCH2CH2CCH3CH3 OCH2CH2CCH3NNOC.CH3CH3 OCH2CH2CCH3CH3NOOD.CH3CH3OCH3 OCH2CH2CCH3NNCH2CH2CCH3OHO名师归纳总结 22.O EtOH,H SOCl 2 第 6 页,
9、共 9 页OLiAlH 4 CH 2COOEt 2EtONa- - - - - - -精选学习资料 - - - - - - - - - A.OCH2OHCH2ClCOOEtOCH2OHCOOEtCH2OHOB.OCH2OHCH2ClCOOEtOCH2OHCH2ClO23.OCH2OHCH2ClC HPhClCOOEtC.OCH2ClCOOEtCH2OHOCH2OHCH2ClCOOEtOD.OCH2OHCOOEtCH2OHOPhMgBrOH3O PBr 3 PPh3 NaOHC HCHO CHCH2Ph PPh3C HA.PhCHCH2OHPhCHCH2BrPh3PC HOHBrPh24.B.P
10、hCHCH2PhCHCH2BrPh3P CCH2PhH2CC HC HC HBrBrPhC HCHCHCH 2PhC.PhCHCH3PhCHCH3CH3CPhCH3COHBrPPh3D. PhCH2CH2OHPhCH2CH2BrPh3PCHCH 2Ph+ HCHO +CH 32NH OH名师归纳总结 A.CH2NCH 32B.CH 2NCH 32C.OHCH2NCH 32D.OHCH 2NCH 32第 7 页,共 9 页OHH3C2NH 2COH- - - - - - -精选学习资料 - - - - - - - - - 25.+COOCH 3 A.H3CCOOCH 3H3CCOOCH3H3CC
11、OOCH3D.H3CCOOCH3B.C.26.H3CCH 3H3CCH3H3CCH3H3CCH3CH 2CHCHCH 32H+,加热 OH27.A.CH2CHCHCH 3B.CH2CH3CHCH32C.D.CH2CH2CHCHCHCH 32OHOCH3CH 2CCl, AlCl 3 CH3A.OHOCH2CH 3B.OHCCH2CH3C.OCH2CH3D.OHCCH2CH3OCCH3CH3H2CCCH3OOO28.NHKOH BrCH 2CH2CH2CH 3 C2H5OHO名师归纳总结 A.NaOH + COONaCH3CH2CH2CH2NH2第 8 页,共 9 页 H 2OOONKNCH2C
12、H2CH2CH3COONaB.OO OCOONaCH3CH2CH2CH2NH2OOKNHCH 2CH2CH2CH3OKNHCH 2CH2CH2CH3COONaC.OOCOOHOOOOHNOHNHCH 2CH2CH2CH3CH3CH2CH2CNH2COOHOO- - - - - - -精选学习资料 - - - - - - - - - OOO名师归纳总结 D.A.ONHCH 2CH 2CH2CH 3ONaCH 3CH 2CH 2CH 2NH 2第 9 页,共 9 页29.COOHCOONaOO+H 2CCHCOCH3KOH H2CPC 6 H53 KOHOHOOHB.O30.C.OOOCH2D.OCH 2CH 3ONaOEt OH H + C+ ClCH 2COEtA.OHClCOOC2H5OCHCOOHB.CH3COOC2H5OHH 2 CCOOHCCH3CH3CH3COOC2H 5CH3D.OCOOC2H5CH 3OC.CHCH 2OHCH3CHCHOCH 3- - - - - - -